Dental and Periodontal Changes After Accelerated Correction of Lower Anterior Teeth Crowding With Periodontally Accelerated Osteogenic Orthodontics (PAOO) Procedure: A Randomized Controlled Trial.

Objective To evaluate the relative efficacy of periodontally accelerated osteogenic orthodontics (PAOO) compared to conventional fixed appliances in correcting lower anterior teeth crowding using a non-extraction treatment approach. Material and methods A single-center, two-arm, parallel-group randomized controlled trial was conducted on 38 patients (9 males, 29 females) with moderate crowding. These patients did not require premolar extraction and were randomly allocated into two treatment groups: the PAOO group and the conventional orthodontic treatment group. The Little Irregularity Index (LII) measured crowding intensity on pre-treatment study models. Changes in this index were recorded monthly in both treatment groups. The inter-canine width, inter-second-premolar width, plaque index (PI), gingival index (GI), and papillary bleeding index (PBI) were also measured before and after the leveling and alignment stage. Statistical analysis between the two groups was performed using Mann-Whitney U tests. Results For the LII, the average time for irregularity resolution was three months in the PAOO group, compared to five months in the conventional orthodontic treatment group. Regarding changes in inter-second-premolar width, the PAOO procedure led to a significant decrease in the increase of inter-second-premolar width, with an average increase of +1.52 mm compared to +2.71 mm in the control group. For the GI and PBI, it was found that their values significantly increased with PAOO application, averaging 0.18 and 0.17, respectively, compared to 0.05 and 0.07 in the control group. Conclusions The use of PAOO in orthodontic treatment accelerated the leveling and alignment process by 40%. Changes in the inter-canine width, the inter-second-premolar width, and the status of periodontal tissues were minimal and clinically negligible.

Modelling Asphalt Overlay As-Built Roughness Based on Profile Transformation-Case for Paver Using Automatic Levelling System.

The as-built roughness, or smoothness obtained during pavement construction, plays an important role in road engineering since it serves as an indicator for both the level of service provided to users and the overall standard of construction quality. Being able to predict as-built roughness is therefore important for supporting pavement design and management decision making. An as-built IRI prediction model for asphalt overlays based on profile transformation was proposed in a previous study. The model, used as basis for this work, was developed for the case of wheeled pavers without automatic screed levelling. This study presents further development of the base prediction model, including the use of an automatic screed control system through a long-distance averaging mobile reference. Formulation of linear systems that constitute the model are presented for the case of a wheeled paver using contactless acoustic sensors set-up over a floating levelling beam attached to the paver. To calibrate the model, longitudinal profile data from the Long-Term Pavement Performance SPS-5 experiment was used, obtaining a mean error of 0.17 m/km for the predicted IRI. The results obtained demonstrate the potential of the proposed approach as a modelling alternative.

Curve of Spee modification in different vertical skeletal patterns after clear aligner therapy: a 3D set-up retrospective study.

OBJECTIVE: The purpose of the present study was to evaluate: (1) changes in the curve of Spee (COS) after clear aligner therapy and (2) whether such changes correlated with the patient's skeletal patterns. MATERIALS AND METHODS: Three-dimensional mandibular models of 106 patients (47 males and 59 females; mean age 22.3 SD ± 3.4 years) treated with clear aligners were retrospectively analysed. The perpendicular distance between the occlusal reference plane and the buccal cusp tip of each lateral tooth was measured. Five angular cephalometric measurements (PP-MP, PP-OP, OP-MP, AFH, and PFH) were performed and correlated with the T1-T0 difference in linear distances. The patients were divided into three groups according to facial divergence. Variance analysis with Tukey post hoc correction was performed to evaluate the differences among groups. RESULTS: The one-way ANOVA test showed a statistically significant difference for all analysed variables, except for the change in the distance of the second molar from the occlusal reference plane. Tukey's HSD test showed the following differences: In normodivergents, the T1-T0 difference in the distance of the first molar from the occlusal plane was 1 mm greater than that observed in the hyperdivergent group (p < 0.05); in the normodivergent group, the T1-T0 difference in the distance of the second premolar from the occlusal plane was 1.23 mm greater than that observed in the hyperdivergent group (p < 0.05), while in the hypodivergent group, it was 1.08 mm greater than in the hyperdivergent group (p < 0.05); finally, in normodivergents, the T1-T0 difference in the distance of the first premolar from the occlusal plane was 0.97 mm greater than that observed in the hyperdivergent group (p < 0.05). CONCLUSION: Treatment with aligners did not lead to a clinically significant change in COS depth. However, when dividing the sample into groups based on craniofacial divergence, COS depth change differed significantly between the three groups.

Surface Defect Mitigation of Additively Manufactured Parts Using Surfactant-Mediated Electroless Nickel Coatings.

The emergence of defects during the early production phases of ferrous-alloy additively manufactured (AM) parts poses a serious threat to their versatility and adversely impacts their overall mechanical performance in industries ranging from aerospace engineering to medicine. Lack of fusion and gas entrapment during the manufacturing stages leads to increased surface roughness and porosities in the finished part. In this study, the efficacy of employing electroless nickel-boron (Ni-B) deposition to fill and level simulated AM defects was evaluated. The approach to levelling was inspired by the electrochemical deposition techniques used to fill vias in the electronics industry that (to some extent) resemble the size and shape of AM-type defects. This work investigated the use of surfactants to attenuate surface roughness in electroless nickel coatings, thereby achieving the preferential inhibition of the coating thickness on the surface and promoting the filling of the simulated defects. A cationic surfactant molecule, CTAB (cetyltrimethyl ammonium bromide), and a nonpolar surfactant, PEG (polyethylene glycol), at different concentrations were tested using a Ni-B electrolyte for the levelling study. It was found that the use of electroless Ni-B to fill simulated defects on ferrous alloys was strongly influenced by the concentration and nature of the surfactant. The highest levelling percentages were obtained for the heavy-molecular-weight PEG-mediated coatings at 1.2 g/L. The results suggest that electroless Ni-B deposition could be a novel and facile approach to filling defects in ferrous-based AM parts.

Investigation of Forces and Moments during Orthodontic Tooth Intrusion Using Robot Orthodontic Measurement and Simulation System (ROSS).

The Robot Orthodontic Measurement and Simulation System (ROSS) is a novel biomechanical, dynamic, self-regulating setup for the simulation of tooth movement. The intrusion of the front teeth with forces greater than 0.5 N poses a risk for orthodontic-induced inflammatory root resorption (OIIRR). The aim was to investigate forces and moments during simulated tooth intrusion using ROSS. Five specimens of sixteen unmodified NiTi archwires and seven NiTi archwires with intrusion steps from different manufacturers (Forestadent, Ormco, Dentsply Sirona) with a 0.012″/0.014″/0.016″ wire dimension were tested. Overall, a higher wire dimension correlated with greater intrusive forces Fz (0.012″: 0.561-0.690 N; 0.014″: 0.996-1.321 N; 0.016″: 1.44-2.254 N) and protruding moments Mx (0.012″: -2.65 to -3.922 Nmm; 0.014″: -4.753 to -7.384 Nmm; 0.016″: -5.556 to -11.466 Nmm) during the simulated intrusion of a 1.6 mm-extruded upper incisor. However, the 'intrusion efficiency' parameter was greater for smaller wire dimensions. Modification with intrusion steps led to an overcompensation of the intrusion distance; however, it led to a severe increase in Fz and Mx, e.g., the Sentalloy 0.016″ medium (Dentsply Sirona) exerted 2.891 N and -19.437 Nmm. To reduce the risk for OIIRR, 0.014″ NiTi archwires can be applied for initial aligning (without vertical challenges), and intrusion steps for the vertical levelling of extruded teeth should be bent in the initial archwire, i.e., 0.012″ NiTi.

Positional Goods and Social Equality: Examining the Convergence Thesis.

Several philosophers argue for the 'convergence thesis' for positional goods: prioritarians, sufficientarians, and egalitarians may converge on favouring an equal (or not too unequal) distribution of goods that have positional aspects. I discuss some problems for this thesis when applied to two key goods for which it has been proposed: education and wealth. I show, however, that there is a variant of the thesis that avoids these problems. This version of the thesis is significant, I demonstrate, because it applies to a person's status as a citizen, which I suggest is the central concern of social or 'relational' egalitarianism.

Modular UV Curing Sol-Gel Coating for Invisible, Levelling and Easy to Clean Multi-Layer Systems.

Current methods for the hardening step of functional coatings over different materials imply the use of high temperatures, high energy consumption or long periods of time, which have repercussions on the speed and cost of the product. We report here a simple and low-cost methodology for the functionalization of low-cost stainless steel, which is modular, depending on the functionality pursued: a levelling layer for smoothing the surface of the material, an "easy to clean" property, or both of them. This research is based on sol-gel coatings cured under UV light without requiring high thermal hardening processes, making it applicable to plastics and other sensible materials and possessing high chemical and thermal stability. The film ensures lower processing costs and higher rates of hardening if adequate medium-pressure lamps are employed. This formulation is also well-defined for scaling up the process, so it is possible to perform a continuous coating in large areas by employing mild processing conditions (low temperature, atmospheric pressure). In addition, the sol-gel solution was fully characterized and studied in order to guarantee a long service life before deposition, with a focus on industrial applications in the domestic sector.

Levelling Up for health in towns? Development of a new deprivation index: the 'Stronger Towns Index' and its association with self-rated health and migration in England, between 2001 and 2011.

Aim: To develop the 'Stronger Towns Index': a deprivation index that took into account characteristics of areas encompassing towns that may be eligible for redevelopment funding and explore how this index was associated with self-rated health and migration within England between 2001 and 2011. Subject and methods: All members of the ONS Longitudinal Study in England aged 16 and over in 2001 whose records included a self-rated health response and a valid local authority code.Local authorities in England were ranked using a composite index developed using the five metrics set out in the Stronger Towns Funding: productivity, income, skills, deprivation measures, and the proportion of people living in towns.The index was split into deciles, and logistic regression carried out on the association between decile and self-rated health in 2001 in the main sample (n = 407,878) and decile change and self-rated health in 2011 in a subsample also present in 2011, with migration information (n = 299,008). Results: There were areas in the lowest deciles of Town Strength who did not receive funding. After multiple adjustment, LS members living in areas with higher deciles were significantly more likely (7% to 38%) to report good health than those in the lowest decile in 2001. Remaining in the same decile between 2001 and 2011 was associated with 7% lower odds of good self-rated health in 2011. Conclusion: It is important to consider health in towns when allocating funding. Areas in the Midlands may have missed out on funding which might help mitigate poor health.

On the Consistency between a Classical Definition of the Geoid-to-Quasigeoid Separation and Helmert Orthometric Heights.

It is acknowledged that a classical definition of the geoid-to-quasigeoid separation as a function of the simple planar Bouguer gravity anomaly is compatible with Helmert's definition of orthometric heights. According to Helmert, the mean actual gravity along the plumbline between the geoid and the topographic surface in the definition of orthometric height is computed approximately from the measured surface gravity by applying the Poincaré-Prey gravity reduction. This study provides theoretical proof and numerical evidence that this assumption is valid. We demonstrate that differences between the normal and (Helmert) orthometric corrections are equivalent to the geoid-to-quasigeoid separation differences computed for individual levelling segments. According to our theoretical estimates, maximum differences between these 2 quantities should be less than ±1 mm. By analogy, differences between the Molodensky normal and Helmert orthometric heights at levelling benchmarks should be equivalent to the geoid-to-quasigeoid separation computed from the Bouguer gravity data. Both theoretical findings are inspected numerically by using levelling and gravity data along selected closed levelling loops of the vertical control network in Hong Kong. Results show that values of the geoid-to-quasigeoid separation at levelling benchmarks differ less than ±0.1 mm from differences between the normal and orthometric corrections. Relatively large differences (slightly exceeding 2 mm) between values of the geoid-to-quasigeoid separation and differences between the normal and (Helmert) orthometric heights at levelling benchmarks are explained by errors in levelling measurements rather than by inconsistencies in computed values of the geoid-to-quasigeoid separation and (Helmert) orthometric correction.

Economic Considerations on Costs and Pricing of Two Surgical Techniques for Treating Cranial Cruciate Disease in Dogs.

In surgical treatment of cranial cruciate ligament disease in dogs, Tibial Plateau Levelling Osteotomy (TPLO) and Tibial Tuberosity Advancement (TTA) are commonly established procedures and have proven effective in restoring limb function. Unlike clinical outcome, economic aspects have not been studied as extensively. However, the surgical intervention poses an enormous financial burden on patients' owners. In a veterinary practice setting, this study compares prices for TPLO and TTA and examines prices differences as well as potential cost drivers. Charges for veterinary treatments are based on the Gebührenordnung für Tierärztinnen und Tierärzte (GOT), which is mandatory for veterinarians in Germany but allows a certain range in billing. This study found that TPLO is charged at a higher price than TTA; however, this might not cover the additional costs of this procedure. The price is also associated with weight, heavier dogs being more expensive. The underlying strategies for pricing decisions may be based on costs, as efforts for TPLO and heavier dogs are higher in terms of a prolonged surgical time, the number of staff involved and in surgeons' training. Price setting may also be based on a quality promise, suggesting better clinical outcome in a more expensive procedure. Future investigations should involve economic considerations and consider cost-effectiveness analysis when evaluating surgical treatment options.

Learning pathways: Levelling, scaffolding & mapping curriculum.

At one mid-sized research-intensive university in Western Canada, the Bachelor of Science in Nursing (BSN) program recently underwent significant curriculum revisions (Epp et al., 2021). A constructivist approach was adopted to create opportunities for students to align knowledge, skills, and abilities (KSA) with prior learning to build a deeper understanding (Vygotsky, 1978). In congruence with constructivist theory, faculty developed several learning pathways as curriculum planning tools to strategically sequence student learning outcomes, facilitate student achievement of program learning outcomes, and improve curriculum integrity. The faculty developed a conceptual model of a learning pathway and identified several key program outcomes that would benefit from a curriculum review to ensure these concepts were adequately covered across the nursing program. Each learning pathway details curriculum mapping of the levelling and scaffolding of specific concepts and content to facilitate students in the acquisition of KSA through a progressive approach (Gazza & Hunker, 2012; Maguire, 2013). This article will profile the BSN Scholarly Writing Pathway and the BSN Psychomotor Pathway as exemplars.

Effect of Roller Levelling on Tensile Properties of Aluminum Sheets.

The straightening of sheets, bars and profiles plays an important role in many machining processes. The aim of sheet straightening in the rolling mill is to ensure that the deviation of sheets from flatness is within the tolerances specified in the standards or delivery conditions. There is a wide range of information available on the roller levelling process used to meet these quality requirements. However, little attention has been paid to the effects of levelling, namely the change in properties of the sheets before and after roller levelling. The aim of the present publication is to investigate how the levelling process affects tensile test results. The experiments have shown that levelling increases the yield strength of the sheet by 14-18%, while it decreases its elongation by 1-3% and hardening exponent by 15%. The mechanical model developed allows changes to be predicted, so that a plan can be made regarding roller levelling technology that has the least effect on the properties of the sheet while maintaining the desired dimensional accuracy.

Placemaking and infrastructure through the lens of levelling up for health equity: A scoping review.

The planning and delivery of infrastructure influences how places create health equity. The scholarship on place and health has recently been developed into 'levelling up' principles for equity focussed policy and planning. We conducted a scoping review of the literature on infrastructure through urban regeneration and placemaking interventions. We interrogated the 15 final selected articles for their use of one or more of the five 'levelling' up principles. No article encompassed all five principles. It was most common to find two or three principles in action. Reviewing the articles against the principles allows a deeper explanation of how infrastructure planning practice can positively impact on health equity. We conclude that applying all the principles in standard infrastructure planning practice has great potential for creating places that are positive for health equity.

Pharma 4.0: analysis on core competence and digital levelling implementation in pharmaceutical industry in Indonesia.

Purpose: This paper aims to explore core competencies and analyze the digital leveling implementation of Pharma 4.0 in Indonesian Pharmaceutical companies. Method: This study uses a mixed-method Delphi study conducted in the first two rounds. The first and second rounds aimed to determine the core competencies of the Pharmaceutical Industry to face the Pharma 4.0 era. In the first round, FGD was conducted involving 12 participants, and semi-structured interviews were carried out with 10 participants in the second round. Alongside Delphi, this research also employs NVIVO as a tool for content analysis. Furthermore, in the third round, a survey was conducted to determine the leveling of the digital implementation of Pharma 4.0, involving 215 senior management participants representing 34 national pharmaceutical industries. Result: The study revealed eight core competencies needed by human capital in the pharmaceutical industry to face the Pharma 4.0 era: critical thinking, bioinformatics, entrepreneurial thinking, digital skills, intrapreneurial skills, research skills, regulatory compliance, and data ethics. Regarding digital leveling implementation, this study found five main levels: level 1 (simplification), level 2 (automatization), level 3 (integrated system), level 4 (digital transformation), and level 5 (disease prediction). This study also affirms that most of the pharmaceutical industries in Indonesia are at level 2 (mean = 4.2) and level 1 (mean = 4.0). Several pharmaceutical industries are at level 3 (mean = 3.5), and a few others are at level 4 (mean 3.2) and level 5 (mean = 1.4). Research implication: This study is the first to analyze the leveling of digital implementation in Pharma 4.0. The results showed that core competencies could be used as a benchmark to develop employee skills. This current study provides the essential data for core competency development and digital leveling implementation for the pharmaceutical industry and government in preparing Pharma 4.0.

Association of Craniofacial Patterns with the Curve of Spee and the Time Required for Orthodontic Levelling.

The curve of Spee (CoS) is an important parameter for an individualized treatment plan. The available information regarding a potential association of the depth of the curve of Spee with various skeletal craniofacial characteristics is conflicting and it is also unknown whether certain craniofacial parameters affect the duration of the levelling phase of orthodontic treatment. A prospective sample of 32 patients with mild to moderate crowding that underwent orthodontic treatment with full fixed appliances was used to study these topics. The craniofacial characteristics were captured on pre-treatment lateral cephalometric radiographs and measurements of the CoS were performed on the initial 3D digital dental models using the Viewbox 4 software. Non-parametric statistics and Spearman's correlations were applied. Weak negative correlations were detected between the CoS depth and the SNA and SNB angles. There was no other association between the CoS and craniofacial parameters, including various anteroposterior measurements. Furthermore, there was no significant association of any craniofacial parameter with the duration of the levelling. Contrary to certain clinical beliefs, it can be argued that the craniofacial characteristics are not associated with the CoS and the time required for its levelling in subjects with moderate pre-treatment CoS depth.

Levelling up health: A practical, evidence-based framework for reducing health inequalities.

There are substantial inequalities in health across society which have been exacerbated by the COVID-19 pandemic. The UK government have committed to a programme of levelling-up to address geographical inequalities. Here we undertake rapid review of the evidence base on interventions to reduce such health inequalities and developed a practical, evidence-based framework to 'level up' health across the country. This paper overviews a rapid review undertaken to develop a framework of guiding principles to guide policy. To that end and based on an initial theory, we searched one electrotonic database (MEDLINE) from 2007 to July 2021 to identify published umbrella reviews and undertook an internet search to identify relevant systematic reviews, primary studies, and grey literature. Titles and abstracts were screened according to the eligibility criteria. Key themes were extracted from the included studies and synthesised into an overarching framework of guiding principles in consultation with an expert panel. Included studies were cross checked with the initial theoretical domains and further searching undertaken to fill any gaps. We identified 16 published umbrella reviews (covering 667 individual studies), 19 grey literature publications, and 15 key systematic reviews or primary studies. Based on these studies, we develop a framework applicable at national, regional and local level which consisted of five principles - 1) healthy-by-default and easy to use initiatives; 2) long-term, multi-sector action; 3) locally designed focus; 4) targeting disadvantaged communities; and 5) matching of resources to need. Decision-makers working on policies to level up health should be guided by these five principles.

Influence of tibial plateau levelling osteotomy on the tensile forces sustained by ligaments in cranial cruciate ligament-intact canine stifles: An ex vivo pilot study.

BACKGROUND: Tibial plateau levelling osteotomy (TPLO) changes the anatomical tibial conformation and might alter the positional relationship of the ligaments comprising the stifle joint. As a result, it is expected to affect the tensile force of the ligaments. However, studies analyzing the details of the effect of osteotomy are limited. OBJECTIVES: To evaluate the influence of TPLO on the tensile force on the stifle ligaments in the intact canine stifle using a six-degree-of-freedom (6-DOF) robotic testing system. METHODS: Eight stifles were categorised into the reference group and nine stifles into the TPLO group. The stifles were then analysed using a 6-DOF robotic joint biomechanical testing system. The stifles were applied 30 N at cranial, caudal, and compression loads and 1 Nm at the internal and external torque loads (the load applied to the tibia relative to the femur) on extension, at 135° and 120°, respectively. The tensile force placed on the cranial cruciate ligament (CrCL), the caudal cruciate ligament, the medial collateral ligament, lateral collateral ligament and the total tensile force placed on the four ligaments was calculated under each load. RESULTS: For the caudal load applied to the tibia relative to the femur, the CrCL tensile force in the TPLO group was lower than that in the reference group at 120° (p = 0.02). The CrCL tensile force in the TPLO group was lower than that in the reference group at 120° (p < 0.01) for the compression load. Regarding the cranial, internal, and external load, the CrCL tensile force remains unchanged between both groups at each angle. CONCLUSIONS: TPLO reduces CrCL tensile force during compression and caudal force application. TPLO may reduce tensile forces contributing to CrCL rupture.

Decreasing the degree of polymerization of microcrystalline cellulose by mechanical impact and acid hydrolysis.

Depolymerization of cellulose is often used as a (pre)treatment protocol within the catalytic valorization strategies of cellulose. Typical depolymerization protocols yield polymerization degrees above 70 anhydroglucose units (AGU). However, shorter cellulose fibers are of interest in the search for accessible dietary fiber additives or renewable materials with distinct mechanical properties (bio-composites). In this work, short-polymer microcrystalline celluloses (SMCC) with an average polymerization degree between 29 and 70 AGU were produced with material yields of 95 % and above by combining a planetary ball mill pretreatment with mild acid hydrolysis. By first decreasing the levelling-off degree of polymerization (LODP) with an intensive ball mill treatment, a mild acid hydrolysis protocol was sufficient to ensure high yields of SMCC. Furthermore, the desired polymerization degree could be obtained by tuning the process parameters.

Cross-validated multi-technique geodetic dataset of the Upper Adriatic Sea coastal area of Italy.

The geodetic dataset used in the research article entitled "Multi-technique geodetic detection of onshore and offshore subsidence along the Upper Adriatic Sea coasts"[1] is presented here. It consists of the outcomes of three different techniques, i.e. Synthetic Aperture Radar Interferometry (InSAR), Global Navigation Satellite System (GNSS) and topographic Levelling surveys. This dataset has been used for the estimation of onshore and offshore deformation in a mineral concession area located along the Upper Adriatic Sea coastal area (Italy), South-East of Ravenna city. InSAR data covers the period from 2002 to 2018, GNSS data from 1998 to 2018 and levelling data from 2002 to 2017.The different measurements have been cross-validated and referred to a common local reference system fixed in the urban area of Ravenna. This data collection will be very useful for deepening the analysis of any type of deformation in the Ravenna coastal area.

Retrospective comparison of outcomes following tibial plateau levelling osteotomy and lateral fabello-tibial suture stabilisation of cranial cruciate ligament disease in small dogs with high tibial plateau angles.

AIMS: To compare short and long-term outcomes after tibial plateau levelling osteotomy (TPLO) and lateral fabello-tibial suture (LFTS) techniques for the management of cranial cruciate ligament disease in small dogs with high tibial plateau angles (TPA). METHODS: In this retrospective study, the medical records of two veterinary specialist practices in the United Kingdom were searched for dogs (<20 kg) that underwent TPLO or LFTS between 2000 and 2010, and had a preoperative radiographic TPA >30° with either short-term (6 weeks) and/or long-term (>3 months) follow-up data. Data collected at a 6-week post-surgical re-examination was derived from orthopaedic examination and radiographic assessment and included the incidence of major and minor complications and scoring of the short-term outcome. Long-term outcome was scored based on results of a subjective owner questionnaire and veterinary orthopaedic examination. RESULTS: A total of 61 (84 stifles) dogs were included in the study: 24 (30 stilfes) and 37 (54 stifles) dogs underwent LFTS and TPLO, respectively. Long-term clinical outcome was different (p = 0.017) between groups; 15/15 stifles in the TPLO group had a good or excellent long-term clinical outcome, compared to 4/8 (50%) in the LFTS group. There was no evidence of a difference in short-term post-operative outcome or owner subjective long-term outcome between treatment groups.Stifles in the LFTS group were more likely (p = 0.027) to have palpable stifle pain at long-term follow-up. Owners reported that 5/16 (31.3%) dogs in the LFTS group required oral non-steroidal anti-inflammatory drug (NSAID) treatment at least monthly (4/5 required daily treatment), whereas no dogs in the TPLO group required treatment with NSAID more frequently than three times per year (p = 0.011).No correlation was found between short-term outcome and owner subjective long-term outcome but there was a positive correlation between short-term outcome and long-term clinical outcome.There was no evidence of a difference in overall major complication rates between treatment groups. The occurrence of complications was associated with heavier body weight at the time of surgery. No other variables were shown to be risk factors for complications. CONCLUSION AND CLINICAL RELEVANCE: Small breed dogs with high TPA that underwent TPLO had better long-term clinical outcomes and were less likely to require NSAID administration than those that underwent LFTS. The risk of complication increased with the weight of the dog at surgery. There was a positive correlation between short-term outcome and long-term clinical outcome.